09/29/2025
# Epithelial Bullae after Cataract surgery:
Epithelial bullae after cataract surgery as pseudophakic bullous keratopathy (PBK), are painful, fluid-filled blisters on the cornea resulting from the irreversible damage to the corneal endothelium, the vital pump that keeps the cornea clear. This endothelial damage, a complication of cataract surgery (especially phacoemulsification), leads to corneal swelling (edema) that eventually causes the overlying epithelial layer to separate and form these bullae. Symptoms include pain, redness, watering, and worsening vision, and the condition may require hypertonic drops, therapeutic contact lenses, or ultimately corneal transplantation.
Causes
Endothelial Trauma: Damage to the corneal endothelium from surgical instruments, the intraocular lens (IOL), or excessive ultrasound energy (phaco power) is a primary cause.
Pre-existing Conditions: Patients with conditions like Fuchs' endothelial dystrophy have a lower endothelial cell count and are at higher risk.
Severe post-operative inflammation or infection can also contribute.
Technical Issues: Improper placement of surgical tools, like the phaco probe, can cause the epithelium to lift and form a bubble during surgery.
Symptoms
Pain and Discomfort: Ruptured epithelial bullae expose corneal nerve endings, leading to pain.
Vision Loss: Corneal edema can cause blurry vision and glare.
Eye redness and excess watering are common symptoms.
Treatment. :
Conservative Management:
Hypertonic Agents: Topical hypertonic drops or ointments, such as 5% sodium chloride, are used to draw fluid out of the swollen cornea.
Cycloplegics and Antiglaucoma Drugs: These medications may be used to manage symptoms.
Therapeutic Contact Lenses: These can help relieve discomfort and protect the eye surface.
Surgical Treatment:
Corneal Transplantation: In severe or irreversible cases, a corneal transplant is the last option.
Rabisankar Maity
Eye sight